#4958 IMPROVEMENT OF NUTRITIONAL STATUS AFTER PARATHYROIDECTOMY IN PATIENTS RECEIVING MAINTENANCE HEMODIALYSIS

Abstract Background and Aims Improvement in quality of life survival have been reported after parathyroidectomy patients with end-stage kidney disease. In addition to bone loss, protein-energy wasting has also linked excess parathyroid hormone (PTH) level. The present study examined the changes nutritional parameters receiving maintenance hemodialysis compared non-parathyroidectomized patients. Method One hundred eighty-seven who underwent during 2012–2018 were identified (PTX group) matched 1:1 479 levels ≤1000 pg/mL (non-PTX control 187 PTH >1000 (pre-PTX by propensity score. matchings yielded 120 pairs from PTX non-PTX groups (cohort 1) 76 pre-PTX 2). Baseline follow-up data over 12-month period. Results cohort 1, substantially lower serum albumin creatinine/body surface area (Cr/BSA) higher proportions ≤38 g/L (low albumin) Cr/BSA ≤380 μmol/L/m2 Cr/BSA) observed group. These percentage total lymphocyte count <800 cells/mm3 TLC) improved parathyroidectomy. At follow-up, albumin, low became comparable TLC was at Mixed-models analysis confirmed significant differences Cr/BSA, between two groups. 2, there no difference baseline parameters. body mass index (BMI) ≤18.5 kg/m2, Weight gain more frequent greater magnitude group both cohorts. Higher level, creatinine significantly associated ≥10% increase BMI. Conclusion Parathyroidectomy improvement severe hyperparathyroidism.